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Relapsed or Refactory

Criteria to qualify for study: Drug used in study:
  • Must be CD5, CD19/20, and CD23 positive
  • Cannot have more than 55% of circulating lymphocytes
  • Lymphocyte count at diagnosis must be at least 5 x 103/µL

CLL 23 SCRI GP28331 Genentech

A Phase Ib Multicenter Dose-Finding and Safety Study of GDC-0199 and Obinutuzumab in Patients with Relapsed or Refractory or Previously Untreated Chronic Lymphocytic Leukemia (CLL)

Criteria to qualify for study: Drug used in study:
  • Patient cannot have Richter's syndroms
  • Patient cannont have undergone prior allogeneic stem cell transplant
  • Patient cannot be receiving a strong CYP3A4 inhibitor or inducer or a proton pum inhibitor (PPI) or Acid Reducing Agent (ARA)

HEMREF 35 SCRI Portola PRT062070

A Phase I Open-Label, Multi-Dose, Dose Escalation Study of PRT062070 in Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) or B-Cell Non-Hodgkin Lymphoma (NHL)